INT229476

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.60
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ndel1) transport (Ndel1) nuclear envelope (Ndel1)
chromosome segregation (Ndel1) chromosome (Ndel1) cytoskeleton (Ndel1)
Anatomy Link Frequency
sciatic nerve 1
nerve 1
Ndel1 (Mus musculus)
Pain Link Frequency Relevance Heat
Sciatic nerve 93 97.16 Very High Very High Very High
dorsal root ganglion 57 86.80 High High
Spinal cord 30 17.52 Low Low
butorphanol 3 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
Dorsal column 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 9 89.28 High High
Ganglion Cysts 66 86.80 High High
Embryonic Lethality 6 85.76 High High
Injury 63 73.92 Quite High
Infection 3 53.08 Quite High
Nervous System Injury 6 41.68 Quite Low
Coronary Artery Disease 9 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The up-regulation of Ndel1 in regenerating nerve axons was further verified by co-staining with Neurofilament antibodies, followed by Z-stack sectioning on confocal microscopy (Fig. 2F).
Regulation (regulation) of Ndel1 in nerve
1) Confidence 0.43 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.13 Pain Relevance 0.06
The control (scrambled) siRNA or Ndel1 siRNA were commercially produced according to the manufacturer's protocol, with a fluorescent tag placed at the 3?
Regulation (control) of Ndel1 siRNA
2) Confidence 0.43 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.21 Pain Relevance 0.08
Mice lacking NF-L, another binding partner for Ndel1 differentially regulated during axon regeneration, exhibit delayed axon regeneration following sciatic nerve crush [32].
Regulation (regulated) of Ndel1 in sciatic nerve associated with sciatic nerve
3) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.26 Pain Relevance 0.10

General Comments

This test has worked.

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