INT229957

Context Info Confidence 0.25 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.70 Pain Relevance 0.03

extracellular region (CD55) plasma membrane (CD55)

Anatomy Link Frequency cornea 2 CD55 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 17 69.56 alcohol 3 5.00 eye pain 1 5.00 Nicotine 1 5.00 Inflammatory response 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Disease 12 80.08 Corneal Disease 4 71.52 Cold Sores 1 69.84 INFLAMMATION 18 69.56 Keratitis 6 69.36 Infection 4 68.92 Herpes Zoster 1 68.16 Conjunctiva Disease 1 67.04 Bacterial Infection 2 59.72 Uveitis 55 42.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thus, in the absence of a very high expression of CRegs on the corneal epithelium, bacterially induced loss of DAF and CD59 could be deleterious to the cornea and lead to vision loss after the putative pathogen has been destroyed by the complement system.

Positive_regulation (induced) of Negative_regulation (loss) of DAF in cornea

1) Confidence 0.25 Published 2008 Journal Semin Immunopathol Section Body Doc Link PMC2315691 Disease Relevance 0.70 Pain Relevance 0.03

General Comments

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