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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.90
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TLR2, TLR6) plasma membrane (TLR2, TLR6) intracellular (TLR2, TLR6)
cytoplasm (TLR2)
TLR2 (Homo sapiens)
TLR6 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 3 84.00 Quite High
cytokine 16 77.44 Quite High
chemokine 1 76.32 Quite High
Inflammatory response 6 68.00 Quite High
Inflammation 19 65.16 Quite High
cINOD 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 10 99.64 Very High Very High Very High
Obesity 6 98.20 Very High Very High Very High
Atherosclerosis 8 97.08 Very High Very High Very High
Shock 2 93.28 High High
Injury 3 84.80 Quite High
Cv Unclassified Under Development 3 84.00 Quite High
Myocardial Infarction 4 80.80 Quite High
Alzheimer's Dementia 1 78.20 Quite High
Multibacillary Leprosy 4 73.60 Quite High
Mycobacterium Infection 86 72.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TLR2 (Online Mendelian Inheritancce in Man (OMIM):603028), as a heterodimer with TLR1 (OMIM: 601194) or TLR6 (OMIM: 605403), mediates recognition of several mycobacterial motifs, including lipopeptides, the 19 kDa protein, lipoarabinomannan (LAM) [1],[27],[28].
TLR2 Binding (heterodimer) of TLR6
1) Confidence 0.07 Published 2008 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2330092 Disease Relevance 0.98 Pain Relevance 0.18
TLR2 (in a heterodimeric association with TLR1 or TLR6) recognizes certain lipopeptides, peptidoglycans, and other lipid moieties derived from gram-positive bacteria (5).
TLR2 Binding (association) of TLR6
2) Confidence 0.07 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2518353 Disease Relevance 0.91 Pain Relevance 0.07

General Comments

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