INT231244

Context Info Confidence 0.20 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.57 Pain Relevance 0.17

cytoplasm (Fus, Alms1) intracellular (Fus) cilium (Alms1) DNA binding (Fus) lipid metabolic process (Alms1) RNA binding (Fus)

Fus (Mus musculus) Alms1 (Mus musculus)

Pain Link Frequency Relevance Heat imagery 16 95.52 Thalamus 5 34.64 Hippocampus 6 31.36 ketamine 1 5.00 anesthesia 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Disease 21 97.04 Neurodegenerative Disease 6 87.24 Targeted Disruption 26 85.76 Alzheimer's Dementia 12 80.52 Amyloid Plaque 11 30.60 Sprains And Strains 6 5.00 Purpura 5 5.00 Immunization 2 5.00 Gliosis 1 5.00 Amyloidosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

By overcoming the BBB, FUS-MB may potentiate agents with demonstrated efficacy and could open new avenues of research by reducing the developmental constraints on new Alzheimer's agents.

FUS-MB Binding (overcoming) of BBB

1) Confidence 0.20 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2364662 Disease Relevance 0.57 Pain Relevance 0.17

General Comments

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