INT231922

Context Info Confidence 0.06 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.33 Pain Relevance 0

nucleus (Rxra) enzyme binding (Rxra) DNA binding (Rxra) transcription factor binding (Rxra)

Rxra (Mus musculus)

Pain Link Frequency Relevance Heat cINOD 20 5.00 diclofenac 2 5.00 agonist 2 5.00 tolerance 2 5.00 Inflammation 2 5.00

Disease Link Frequency Relevance Heat Stress 74 98.16 Toxicity 2 31.68 INFLAMMATION 8 5.00 Shock 4 5.00 Repression 2 5.00 Death 2 5.00 Starvation 2 5.00 Infection 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Evidence of elevated JH levels was strongly supported by the temporal suppression of JHE and late induction of RXR (Figure 1), suggesting that JH levels increase in exposed D. magna over time.

Negative_regulation (suppression) of Positive_regulation (induction) of RXR

1) Confidence 0.06 Published 2008 Journal Genome Biol Section Body Doc Link PMC2374704 Disease Relevance 0.17 Pain Relevance 0

Evidence of elevated JH levels was strongly supported by the temporal suppression of JHE and late induction of RXR (Figure 1), suggesting that JH levels increase in exposed D. magna over time.

Negative_regulation (supported) of Positive_regulation (induction) of RXR

2) Confidence 0.05 Published 2008 Journal Genome Biol Section Body Doc Link PMC2374704 Disease Relevance 0.17 Pain Relevance 0

General Comments

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