INT233322

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 6.10
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HIVEP1) intracellular (HIVEP1) DNA binding (HIVEP1)
cytoplasm (HIVEP1)
Anatomy Link Frequency
T-lymphocytes 2
HIVEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 9 94.08 High High
depression 12 92.40 High High
Dismenorea 10 85.92 High High
Inflammation 12 85.20 High High
Rheumatism 6 84.44 Quite High
addiction 4 60.84 Quite High
Central nervous system 21 60.68 Quite High
Potency 7 44.52 Quite Low
antidepressant 1 29.28 Quite Low
Opioid 1 26.64 Quite Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 313 100.00 Very High Very High Very High
Reprotox - General 2 33 100.00 Very High Very High Very High
Disease 19 100.00 Very High Very High Very High
Spinal Cord Diseases 1 97.06 Very High Very High Very High
Reprotox - General 3 1 96.58 Very High Very High Very High
Depression 12 92.40 High High
Rabies Virus Infection 6 91.28 High High
Hypoactive Sexual Desire Disorder 11 90.94 High High
Infection 62 87.44 High High
Reprotox - General 1 13 85.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, [39] found the lectins from R. communis to inhibit HIV-1 reverse transcriptase.
Negative_regulation (inhibit) of Localization (reverse transcriptase) of HIV-1 associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.10 Published 2008 Journal J Ethnobiol Ethnomed Section Body Doc Link PMC2390512 Disease Relevance 1.12 Pain Relevance 0.22
To evaluate inhibition of HIV-1 replication by these three genetic inhibitors, we transduced a CD4+ cell line (CEMx174) with the HIV-shI-GFP, VRX494, or M589 vectors.
Negative_regulation (inhibition) of Localization (replication) of HIV-1 associated with acquired immune deficiency syndrome or hiv infection
2) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2925957 Disease Relevance 0.90 Pain Relevance 0
Following the diagnosis of HIV infection among males, sexual dysfunction results from psychological factors, physical factors, and changes in sexual habits (e.g., adherence to safe sex practices).5 Low sexual desire and erectile dysfunction may be associated with older age and depression in men with HIV.6 Erectile dysfunction may occur as the result of the psychosocial impact of HIV diagnosis5 following the decrease in testosterone levels that accompanies some medications,7 testicular atrophy, or vacuolar myelopathy.8 Highly active antiretroviral therapy (HAART) has previously been shown to provide the best clinical management for HIV-infected patients, as it decreases the prevalence of hypogonadism and advanced HIV disease, which are principal causes of sexual dysfunction in people infected with HIV.7
Negative_regulation (decreases) of Localization (disease) of HIV associated with spinal cord diseases, reprotox - general 2, reprotox - general 3, depression, hypoactive sexual desire disorder, acquired immune deficiency syndrome or hiv infection, disease and infection
3) Confidence 0.03 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2882546 Disease Relevance 3.07 Pain Relevance 0.26
Furthermore, CD16+ monocytes/macrophages can support HIV replication in T-lymphocytes [49] and may be sequestered by tissues expressing the ?
Negative_regulation (support) of Localization (replication) of HIV in T-lymphocytes associated with acquired immune deficiency syndrome or hiv infection
4) Confidence 0.02 Published 2010 Journal Retrovirology Section Body Doc Link PMC2864195 Disease Relevance 1.02 Pain Relevance 0.08

General Comments

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