INT233476

Context Info Confidence 0.39 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.39 Pain Relevance 0.07

signal transduction (Gpr85) plasma membrane (Gpr85) signal transducer activity (Gpr85)

Anatomy Link Frequency leukocyte 2 Gpr85 (Mus musculus)

Pain Link Frequency Relevance Heat Central nervous system 1 96.88 Multiple sclerosis 1 52.64 agonist 6 27.44 Inflammatory response 6 25.48 chemokine 2 20.32 Inflammation 11 5.00 Inflammatory stimuli 4 5.00 adenocard 3 5.00 antagonist 2 5.00 cytokine 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 1 80.80 Mycobacterial Infection 3 73.72 Shock 1 62.40 Multiple Sclerosis 1 56.72 Demyelinating Disease 1 52.64 INFLAMMATION 21 25.08 Necrosis 2 5.00 Cancer 2 5.00 Hypoxia 1 5.00 Repression 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The co-regulated expression of receptors such as Gpr85 in neural tissues and leukocyte populations may provide a mechanism for the neuro-immune cross-talk that has been observed in several studies [41,42].

Regulation (regulated) of Gene_expression (expression) of Gpr85 in leukocyte

1) Confidence 0.39 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.39 Pain Relevance 0.07

General Comments

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