INT234424

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Context Info
Confidence 0.57
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.38
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MYC) chromosome organization (MYC) nucleolus (MYC)
nucleus (MYC) DNA binding (MYC) protein complex (MYC)
MYC (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 4 66.24 Quite High
Potency 1 56.48 Quite High
Inflammation 12 11.12 Low Low
agonist 11 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Intractable pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 60 99.78 Very High Very High Very High
Leukemia 52 95.92 Very High Very High Very High
Malignant Neoplastic Disease 13 93.76 High High
Cancer 33 73.08 Quite High
Li-fraumeni Syndrome 1 55.52 Quite High
Solid Tumor 1 53.84 Quite High
Hematologic Neoplasms 8 53.00 Quite High
Recurrence 1 52.56 Quite High
Disease 16 44.48 Quite Low
Chronic Lymphoid Leukemia 14 39.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
arrest and apoptosis, but also downregulated the expression of c-myc mRNA and protein [187].
Negative_regulation (downregulated) of Transcription (expression) of c-myc associated with apoptosis
1) Confidence 0.57 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408681 Disease Relevance 1.20 Pain Relevance 0.03
It decreases mRNA expression of the c-MYC oncogene, causes cell-cycle arrest at G0-G1 and acts as an inhibitor of a histone deacetylase.
Negative_regulation (decreases) of Transcription (expression) of c-MYC
2) Confidence 0.09 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2993000 Disease Relevance 0.18 Pain Relevance 0.03

General Comments

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