INT234572

Context Info Confidence 0.09 First Reported 2008 Last Reported 2008 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.08 Pain Relevance 0

mitochondrion (MRP63) structural constituent of ribosome (MRP63) ribosome (MRP63) translation (MRP63)

MRP63 (Homo sapiens) MRP63 - A3243G (2)

Pain Link Frequency Relevance Heat Neuritis 2 5.00

Disease Link Frequency Relevance Heat Leber Hereditary Optic Atrophy 10 76.32 Mitochondrial Disorders 18 5.00 Disease 16 5.00 Diabetes Mellitus 6 5.00 Aging 4 5.00 Deafness 4 5.00 Encephalopathy 2 5.00 Coronary Heart Disease 2 5.00 Syndrome 2 5.00 Renal Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These differences apparently demonstrated a link between haplogroups and the A3243G mutation and, therefore, that mitochondrial genetic background had an impact on the A3243G mutation.

Regulation (impact) of A3243G (A3243G)

1) Confidence 0.09 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2409300 Disease Relevance 0.08 Pain Relevance 0

This indicated that mitochondrial genetic background had no impact on mutation events and did not, therefore, affect the mutation rate of position A3243G.

Neg (not) Regulation (affect) of A3243G (A3243G)

2) Confidence 0.09 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2409300 Disease Relevance 0 Pain Relevance 0

General Comments

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