INT234801

Context Info Confidence 0.08 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.64 Pain Relevance 0.15

cytoplasm (RAB3GAP1, RAB3A) nucleolus (RAB3GAP1) mitochondrion organization (RAB3A) plasma membrane (RAB3A) nucleus (RAB3GAP1) GTPase activity (RAB3A)

RAB3GAP1 (Homo sapiens) RAB3A (Homo sapiens)

Pain Link Frequency Relevance Heat Neurotransmitter 1 98.76 lancinating pain 1 72.16 peripheral neuropathy 1 56.92 Pain 1 40.16 cytokine 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Disease 11 92.52 Syndrome 21 86.32 Microphthalmia 1 80.32 Cataract 2 77.12 Optic Atrophy 1 76.00 Hereditary Sensory And Autonomic Neuropathies 5 74.44 Microcephaly 1 72.48 Pain 2 72.16 Congenital Anomalies 3 70.16 Lissencephaly 1 68.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The activity of Rab3 proteins is tightly regulated by Rab3GAP, which specifically converts active Rab3-GTP to the inactive-GDP form.

Rab3GAP Regulation (regulated) of Rab3

1) Confidence 0.08 Published 2008 Journal Eur J Pediatr Section Body Doc Link PMC2413085 Disease Relevance 1.64 Pain Relevance 0.15

General Comments

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