INT235063

Context Info Confidence 0.04 First Reported 2008 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.81 Pain Relevance 0.39

hydrolase activity, acting on glycosyl bonds (Gla) extracellular region (Gla) Golgi apparatus (Gla) lysosome (Gla) cytoplasm (Gla)

Anatomy Link Frequency AGS 2 Gla (Mus musculus)

Pain Link Frequency Relevance Heat Dopamine 115 90.00 Substantia nigra 8 84.32 Ventral tegmentum 8 82.64 midbrain 15 74.32 Inflammation 11 16.48 Eae 7 5.00 Dynorphin 6 5.00 cytokine 4 5.00 monoamine 3 5.00 Serotonin 3 5.00

Disease Link Frequency Relevance Heat Alagille Syndrome 22 100.00 Targeted Disruption 12 95.24 Stomach Cancer 22 84.40 Hypertrophy 3 65.20 Brain Tumor 1 58.04 Apoptosis 11 56.72 Cancer 39 53.40 Necrosis 3 50.00 Helicobacter Infection 5 25.28 Infection 8 18.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

BSR-transfected AGS–GFP cells (Figure 6B), thus suggesting the existence of an NF-?

Positive_regulation (transfected) of Gene_expression (transfected) of AGS in AGS associated with alagille syndrome

1) Confidence 0.04 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.48 Pain Relevance 0

In a previous report we first detected DAT-Cre mediated beta galactosidase expression in a conditional Rosa26LacZ reporter mice at embryonic day 17 [15], suggesting excision of Pten exon5 at around this developmental point.

Positive_regulation (mediated) of Gene_expression (expression) of galactosidase

2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736587 Disease Relevance 0.33 Pain Relevance 0.39

General Comments

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