INT235148

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Context Info
Confidence 0.38
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Atxn1) RNA binding (Atxn1) nucleus (Atxn1)
cytoplasm (Atxn1)
Anatomy Link Frequency
Purkinje cells 2
Atxn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Calcium channel 5 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 28 93.68 High High
Ataxia 33 91.20 High High
Targeted Disruption 8 90.44 High High
Spinocerebellar Ataxia Type 2 17 61.20 Quite High
Retina Disease 3 5.00 Very Low Very Low Very Low
Machado-joseph Disease 3 5.00 Very Low Very Low Very Low
Cerebellar Ataxia 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LANP is expressed predominantly in Purkinje cells, and its interaction with ataxin-1 is significantly stronger when the number of glutamines is increased (Matilla et al 1997).
Positive_regulation (stronger) of ataxin-1 Binding (interaction) of in Purkinje cells
1) Confidence 0.38 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2413192 Disease Relevance 0.74 Pain Relevance 0

General Comments

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