INT235268

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.96
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Acsl1) endoplasmic reticulum (Acsl1) plasma membrane (Acsl1)
peroxisome (Acsl1) ligase activity (Acsl1) lipid metabolic process (Acsl1)
Anatomy Link Frequency
CPA 2
Acsl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 10 95.56 Very High Very High Very High
metalloproteinase 11 50.00 Quite Low
Inflammation 11 15.44 Low Low
cytokine 7 14.40 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colorectal Cancer 32 100.00 Very High Very High Very High
Acute Coronary Syndrome 17 100.00 Very High Very High Very High
Residual Neoplasm 10 99.84 Very High Very High Very High
Cancer 172 95.72 Very High Very High Very High
Stable Angina Pectoris 10 95.56 Very High Very High Very High
Hypertension 2 87.72 High High
Nicotine Addiction 2 86.88 High High
Obesity 3 85.96 High High
Solid Tumor 6 57.44 Quite High
Genetic Translocation 1 53.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations are supported by qRT-PCR using TG or NTG cells isolated by FACS, which show that ALDH1A1 is the predominant cytoplasmic ALDH enzyme in colorectal tumors and its expression is further increased in residual tumor cells following therapy with CPA; consistent with the phenotypic increase in ALDH+ cells among the CoCSC phenotype.
Positive_regulation (increased) of Gene_expression (expression) of FACS in CPA associated with colorectal cancer and residual neoplasm
1) Confidence 0.49 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2413402 Disease Relevance 0.84 Pain Relevance 0
and MMP-9 were significantly increased in ACS group (P < 0.05) (Table 2).
Positive_regulation (increased) of Gene_expression (group) of ACS associated with acute coronary syndrome
2) Confidence 0.12 Published 2010 Journal Clinical Medicine Insights. Cardiology Section Body Doc Link PMC2956475 Disease Relevance 1.12 Pain Relevance 0.17

General Comments

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