INT235758

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 2.16
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Tradd) cytoplasm (Tradd)
Tradd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 27 99.56 Very High Very High Very High
ischemia 86 62.96 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
cerebral cortex 9 5.00 Very Low Very Low Very Low
Intracerebroventricular 9 5.00 Very Low Very Low Very Low
medulla 9 5.00 Very Low Very Low Very Low
cva 9 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 74 99.52 Very High Very High Very High
Stress 11 99.28 Very High Very High Very High
Targeted Disruption 129 86.72 High High
Apoptosis 88 78.00 Quite High
Death 93 74.92 Quite High
Necrosis 11 73.96 Quite High
Cancer 11 73.60 Quite High
Brain Hemorrhage 51 64.16 Quite High
Middle Cerebral Artery Infarction 93 59.60 Quite High
Optic Nerve Injuries 34 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
enhanced expression of TRADD protein without ischemic stress, we sampled cortical tissue from the normally-perfused hemisphere in ischemic animals and found that TRADD was nearly threefold higher in the TNF?
Positive_regulation (enhanced) of Gene_expression (expression) of TRADD protein associated with stress
1) Confidence 0.49 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2583993 Disease Relevance 0.54 Pain Relevance 0.07
The levels of TRADD protein also increased after both injuries in our study.
Positive_regulation (increased) of Gene_expression (levels) of TRADD associated with injury
2) Confidence 0.37 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2426719 Disease Relevance 1.05 Pain Relevance 0
After 3 hours of post-ischemic reperfusion, mean TRADD expression in TNF?
Positive_regulation (mean) of Gene_expression (expression) of TRADD
3) Confidence 0.36 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2583993 Disease Relevance 0.28 Pain Relevance 0.05
Regional expression of TRADD protein was uniformly higher in TNF?
Positive_regulation (higher) of Gene_expression (expression) of TRADD protein
4) Confidence 0.36 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2583993 Disease Relevance 0.29 Pain Relevance 0.05

General Comments

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