INT236006

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HTR1A, Grin2b) embryo development (Grin2b) signal transducer activity (HTR1A)
HTR1A (Homo sapiens)
Grin2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 8 99.20 Very High Very High Very High
fluoxetine 24 89.68 High High
5HT 45 80.52 Quite High
antidepressant 3 65.68 Quite High
Serotonin 30 61.48 Quite High
antagonist 11 50.36 Quite High
Pyramidal cell 20 5.00 Very Low Very Low Very Low
agonist 15 5.00 Very Low Very Low Very Low
Glutamate 7 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 5 5.00 Very Low Very Low Very Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Mental Disorders 2 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Rupture 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our previous study (21) shows that 5-HT1A receptors primarily target NR2B subunit-containing NMDA receptors, consistent with NR2B being the cargo of the microtubule motor KIF17.
5-HT1A Regulation (target) of NR2B associated with nmda receptor
1) Confidence 0.00 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427346 Disease Relevance 0 Pain Relevance 0.33

General Comments

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