INT236015

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.95
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (APP) extracellular matrix organization (APP) DNA binding (APP)
cytoplasm (APP) cytosol (APP) extracellular region (APP)
HIST2H2AA3 (Homo sapiens)
APP (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 3 76.68 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 51 97.72 Very High Very High Very High
Alzheimer's Dementia 108 93.72 High High
Amyloid Plaque 105 87.32 High High
Drug Induced Neurotoxicity 9 63.24 Quite High
Death 15 53.68 Quite High
Aging 3 12.08 Low Low
Disease 3 7.48 Low Low
Neuroblastoma 9 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Hypopigmentation 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
production, we first determined whether H2O2 induces APP expression, thereby promoting A?
H2O2 Spec (whether) Positive_regulation (induces) of Gene_expression (expression) of APP
1) Confidence 0.02 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427353 Disease Relevance 0.05 Pain Relevance 0
FIGURE 2.H2O2 does not induce APP expression or stimulate the activity of ?
H2O2 Neg (not) Positive_regulation (induce) of Gene_expression (expression) of APP
2) Confidence 0.02 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427353 Disease Relevance 0 Pain Relevance 0
It has been reported that H2O2 can induce APP expression and thereby enhance A?
H2O2 Positive_regulation (induce) of Gene_expression (expression) of APP
3) Confidence 0.02 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427353 Disease Relevance 0.90 Pain Relevance 0.04

General Comments

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