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Context Info
Confidence 0.38
First Reported 1986
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.48
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDA) small molecule metabolic process (CDA) extracellular region (CDA)
Anatomy Link Frequency
bladder 1
CDA (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 3 79.92 Quite High
Antiemetics 1 38.40 Quite Low
Analgesic 1 37.76 Quite Low
headache 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bladder Cancer 1 95.68 Very High Very High Very High
Toxicity 4 91.44 High High
Neutropenia 1 90.16 High High
Umbilical Hernia 5 80.56 Quite High
Fatigue 1 78.60 Quite High
Thrombocytopenia 1 78.08 Quite High
Congenital Anomalies 3 77.04 Quite High
Epidermal Cyst 1 74.00 Quite High
Solid Tumor 8 73.24 Quite High
Cyst 2 71.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Known drug interactions may potentially be used to enhance the antitumour activity of a drug--for instance, the administration of tetrahydrouridine (a cytidine deaminase inhibitor) with cytarabine in an attempt to block its rapid inactivation to uridine arabinoside.
Negative_regulation (inhibitor) of deaminase
1) Confidence 0.38 Published 1986 Journal Clin Pharmacokinet Section Abstract Doc Link 2426030 Disease Relevance 0.13 Pain Relevance 0.08
When comparing the CDL with the CDA, CDL took an average of 6 min longer for a unilateral and 8.6 min longer for a bilateral closure than CDA (p < 0.05).
Negative_regulation (closure) of CDA
2) Confidence 0.05 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2710496 Disease Relevance 0.64 Pain Relevance 0
Zebularine is a new oral cytidine analog originally synthesized as a cytidine deaminase inhibitor that has shown to cause demethylation and reactivation of a silenced and hypermethylated p16 gene in human bladder tumor cells grown in nude mice.
Negative_regulation (inhibitor) of deaminase in bladder associated with bladder cancer
3) Confidence 0.01 Published 2006 Journal J Transl Med Section Body Doc Link PMC1413557 Disease Relevance 0.71 Pain Relevance 0

General Comments

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