INT237247

Context Info Confidence 0.27 First Reported 2007 Last Reported 2009 Negated 1 Speculated 0 Reported most in Body Documents 6 Total Number 6 Disease Relevance 4.64 Pain Relevance 1.20

isomerase activity (Mri1) nucleus (Mri1) cytoplasm (Mri1)

Anatomy Link Frequency brain 1 optic nerve 1 Mri1 (Mus musculus)

Pain Link Frequency Relevance Heat imagery 279 100.00 Somatostatin 12 89.84 addiction 3 67.84 positron emission tomography 36 18.68 Inflammation 13 5.00 anesthesia 6 5.00 Pain 6 5.00 Multiple sclerosis 4 5.00 Analgesic 4 5.00 Central nervous system 3 5.00

Disease Link Frequency Relevance Heat Neuroendocrine Cancer 22 99.68 Cancer 459 98.80 Metastasis 91 98.32 Noninfiltrating Intraductal Carcinoma 14 98.20 Atrophy 7 93.76 Breast Cancer 163 91.88 Disease 99 90.56 Confusion 1 85.24 Reprotox - General 1 13 82.96 Necrosis 37 74.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The MRI magnet and the focussed ultrasound system are integrated and controlled by a focussed ultrasound workstation and console (Fig. 2).

Regulation (controlled) of MRI associated with imagery

1) Confidence 0.27 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 0.26 Pain Relevance 0.44

The diagnostic value of MRI for detecting and predicting tumour size of DCIS is still controversial.

Regulation (value) of MRI associated with cancer, noninfiltrating intraductal carcinoma and imagery

2) Confidence 0.16 Published 2008 Journal Eur Radiol Section Body Doc Link PMC2441491 Disease Relevance 1.60 Pain Relevance 0.22

These control nanoparticles did not produce any change in MRI signal.

Regulation (change) of MRI associated with imagery

3) Confidence 0.03 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673971 Disease Relevance 0.46 Pain Relevance 0.20

This was not due to increased number of metastases, but rather a higher concentration of MGd in the brain which allowed for increased sensitivity on MRI.

Regulation (sensitivity) of MRI in brain associated with imagery and metastasis

4) Confidence 0.03 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673824 Disease Relevance 0.90 Pain Relevance 0.16

As a result, 111In-DTPA-D-Phe1-octreotide imaging has been coupled with single photon emission computerized tomography (SPECT) to become the primary imaging and staging modality of patients with GEP neuroendocrine tumors, exceeding the sensitivity of MRI and CT [689,690].

Regulation (sensitivity) of MRI associated with neuroendocrine cancer and imagery

5) Confidence 0.01 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.95 Pain Relevance 0.19

On orbital high-resolution MRI with fast spin-echo, there was no obvious change in signal intensity in the retrobulbar portion of the right optic nerve.

Neg (no) Regulation (change) of MRI in optic nerve

6) Confidence 0.01 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2661005 Disease Relevance 0.46 Pain Relevance 0

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