INT23756

From wiki-pain
Revision as of 04:28, 23 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 1986
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.77
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (REN) extracellular space (REN) extracellular region (REN)
intracellular (REN) response to stress (REN)
Anatomy Link Frequency
plasma 2
REN (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 6 100.00 Very High Very High Very High
Opioid 2 99.76 Very High Very High Very High
narcan 4 97.76 Very High Very High Very High
adenocard 6 94.56 High High
opioid receptor 2 78.52 Quite High
withdrawal 3 62.04 Quite High
anesthesia 1 25.00 Low Low
backache 2 7.40 Low Low
headache 3 5.48 Low Low
fibrosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 3 94.92 High High
Hypertension 48 89.28 High High
Increased Venous Pressure Under Development 11 89.00 High High
Dizziness 9 68.20 Quite High
Heart Rate Under Development 14 63.20 Quite High
Death 13 53.08 Quite High
Diarrhoea 5 43.60 Quite Low
Pathologic Constriction 2 31.80 Quite Low
Hypersensitivity 2 29.24 Quite Low
Pressure And Volume Under Development 40 16.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, on interruption of exercise, opioid antagonism counteracted the inhibition of the plasma renin-angiotensin system by tibalosine, probably through the naloxone-induced increase in epinephrine release.
Regulation (counteracted) of Negative_regulation (inhibition) of renin in plasma associated with narcan and opioid
1) Confidence 0.44 Published 1986 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2429076 Disease Relevance 0 Pain Relevance 0.48
Direct renin inhibitor
Regulation (Direct) of Negative_regulation (inhibitor) of renin
2) Confidence 0.37 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2922316 Disease Relevance 0.17 Pain Relevance 0
The authors concluded that aliskiren, through inhibition of renin, was an effective and safe orally active BP-lowering drug.66
Regulation (effective) of Negative_regulation (inhibition) of renin
3) Confidence 0.37 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2922316 Disease Relevance 0.36 Pain Relevance 0
The long duration of action of aliskiren in part depends on its long elimination half-life and potent renin inhibition.
Regulation (depends) of Negative_regulation (inhibition) of renin
4) Confidence 0.21 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2952455 Disease Relevance 0.06 Pain Relevance 0.06
Inhibition of the renin-angiotensin system using CV-11974 [2-ethoxy-1-((2'-(1-H-tetrazole-5-yl)biphenyl-4-yl) methyl)-1-H-benzimidazole-7-carboxylic acid], a selective AT1 antagonist, did not affect the diuretic action of KW-3902.
Neg (not) Regulation (affect) of Negative_regulation (Inhibition) of renin associated with antagonist
5) Confidence 0.05 Published 1997 Journal Pharmacology Section Abstract Doc Link 9396079 Disease Relevance 0.18 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox