INT238334

Context Info Confidence 0.04 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.14

peptidase activity (ADAMTS5) extracellular region (ADAMTS5) proteinaceous extracellular matrix (ADAMTS5) Golgi apparatus (GOPC) plasma membrane (GOPC) cytoplasm (GOPC)

GOPC (Homo sapiens) ADAMTS5 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 11 99.64 Pain 14 94.36 metalloproteinase 8 5.00 Mechanotransduction 1 5.00

Disease Link Frequency Relevance Heat Tendinopathy 10 5.00 Rupture 4 5.00 Pain 1 5.00 Bone Cancer 1 5.00 Targeted Disruption 1 5.00 Death 1 5.00 Necrosis 1 5.00 Amputation 1 5.00 Cadaver 1 5.00 Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the present study, growth factors and cytokines had differential effects on ADAMTS-1 or ADAMTS-5 mRNA expression (Fig. 6) compared with that of ADAMTS-4 (Fig. 3).

Fig Regulation (effects) of Transcription (expression) of ADAMTS-5 associated with cytokine

1) Confidence 0.04 Published 2008 Journal Matrix Biol Section Body Doc Link PMC2443387 Disease Relevance 0 Pain Relevance 0.14

General Comments

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