INT238621

Context Info Confidence 0.06 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0

intracellular (Cask) protein complex assembly (Cask) protein complex (Cask) cytoplasm (Cask) signal transducer activity (Cask) cytoskeletal protein binding (Sdc2)

Anatomy Link Frequency tails 1 Sdc2 (Mus musculus) Cask (Rattus norvegicus)

Pain Link Frequency Relevance Heat tetrodotoxin 10 5.00 cerebral cortex 3 5.00 Glutamate receptor 3 5.00 midbrain 2 5.00 Calcium channel 2 5.00 Neurotransmitter 1 5.00 GABAergic 1 5.00

Disease Link Frequency Relevance Heat Adhesions 6 81.68 Targeted Disruption 6 5.00 Cleft Palate 2 5.00 Myelodysplastic Syndromes 1 5.00 Aids-related Complex 1 5.00 Apoptosis 1 5.00 Stroke 1 5.00 Cytomegalovirus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The C-terminal tails of syndecan-2 and SynCAM bind to the single PDZ domain of calcium/calmodulin-dependent serine protein kinase (CASK), another MAGUK protein (Hsueh et al., 1998; Biederer et al., 2002).

syndecan-2 Binding (bind) of CASK in tails

1) Confidence 0.06 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2447900 Disease Relevance 0.08 Pain Relevance 0

General Comments

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