INT240880

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Irs1) cytosol (Mapk8, Irs1) signal transduction (Mapk8, Irs1)
nucleus (Mapk8, Irs1) mitochondrion (Mapk8) signal transducer activity (Irs1)
Mapk8 (Mus musculus)
Irs1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 11 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 21 79.96 Quite High
Stress 3 50.00 Quite Low
Impaired Glucose Tolerance 10 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Hyperglycemia 2 5.00 Very Low Very Low Very Low
Adenovirus Infection 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Weight Gain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
JNK reportedly phosphorylates IRS-1 at the Ser307 residue (5,19,20) and stimulates the degradation of IRS-1 (21,22).
JNK Positive_regulation (stimulates) of Protein_catabolism (degradation) of IRS-1
1) Confidence 0.21 Published 2008 Journal Diabetes Section Body Doc Link PMC2494675 Disease Relevance 0.14 Pain Relevance 0

General Comments

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