INT241963

Context Info Confidence 0.03 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.13

plasma membrane (Prkaca, Grm8) nucleoplasm (Prkaca) mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca) signal transducer activity (Grm8)

Prkaca (Rattus norvegicus) Grm8 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Glutamate 44 100.00 Calcium channel 4 90.24 Glutamate receptor 3 50.00 depression 23 25.28 agonist 9 5.00 Action potential 7 5.00 tetrodotoxin 6 5.00 gABA 4 5.00 noradrenaline 3 5.00 Neurotransmitter 3 5.00

Disease Link Frequency Relevance Heat Depression 23 25.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We previously demonstrated that group III mGluR activation enhanced sEPSC frequency by a direct modulation of glutamate release via PKA (Evans et al., 2001).

PKA Positive_regulation (enhanced) of Positive_regulation (activation) of mGluR associated with glutamate

1) Confidence 0.03 Published 2007 Journal Neuroscience Section Body Doc Link PMC2504724 Disease Relevance 0 Pain Relevance 0.13

General Comments

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