INT242170

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (JUP) cell morphogenesis (JUP) structural molecule activity (JUP)
plasma membrane (JUP) cytoskeleton (JUP) nucleus (JUP)
JUP (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 6 37.36 Quite Low
Hippocampus 3 32.48 Quite Low
nMDA receptor 1 7.04 Low Low
Kinase C 13 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 61 99.84 Very High Very High Very High
Drug Induced Neurotoxicity 12 95.80 Very High Very High Very High
Alzheimer's Dementia 5 19.76 Low Low
Apoptosis 13 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low
Toxicity 7 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Amyloid Plaque 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin levels are markedly reduced in AD patients carrying presenilin-1 (PS-1) inherited mutations [29].
Negative_regulation (reduced) of catenin associated with disease
1) Confidence 0.42 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.85 Pain Relevance 0

General Comments

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