INT243524

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (SOX10) cytoplasm (SOX10) cell-cell signaling (NTF3)
signal transduction (NTF3) extracellular region (NTF3) plasma membrane (NTF3)
NTF3 (Homo sapiens)
SOX10 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 99.16 Very High Very High Very High
excitatory amino acid 3 89.16 High High
Inflammation 2 44.44 Quite Low
Glutamate 14 37.12 Quite Low
Hippocampus 15 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
nMDA receptor 6 5.00 Very Low Very Low Very Low
Glutamate receptor 5 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 29 100.00 Very High Very High Very High
Poisoning 23 82.56 Quite High
Hypersensitivity 1 81.36 Quite High
Infection 1 80.24 Quite High
Aging 1 68.52 Quite High
Injury 22 47.04 Quite Low
INFLAMMATION 2 44.44 Quite Low
Death 2 38.64 Quite Low
Cognitive Disorder 5 10.00 Low Low
Convulsion 10 9.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand a significantly increases DOM toxicity was associated with the neurotrophin NT3 and the H1 receptor antagonist terfenadine in vitro exposure [230, 232].


Positive_regulation (increases) of neurotrophin NT3 Binding (associated) of DOM associated with toxicity and antagonist
1) Confidence 0.01 Published 2008 Journal Marine Drugs Section Body Doc Link PMC2525487 Disease Relevance 0.54 Pain Relevance 0.14

General Comments

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