INT243684

Context Info Confidence 0.01 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.10

transport (NDUFA2) mitochondrion (NDUFA2) extracellular space (CXCL16) small molecule metabolic process (NDUFA2) extracellular region (CXCL16) plasma membrane (CXCL16)

Anatomy Link Frequency monocytes 1 CXCL16 (Homo sapiens) NDUFA2 (Homo sapiens)

Pain Link Frequency Relevance Heat aspirin 48 98.92 dexamethasone 5 96.64 Inflammation 30 5.00 cytokine 11 5.00 cINOD 6 5.00 Arthritis 4 5.00 Pain 2 5.00 rheumatoid arthritis 1 5.00 Kinase C 1 5.00 Crohn's disease 1 5.00

Disease Link Frequency Relevance Heat Death 3 71.44 INFLAMMATION 31 5.00 Arthritis 6 5.00 Atherosclerosis 3 5.00 Necrosis 2 5.00 Pain 2 5.00 Atherosclerotic Plaque 2 5.00 Cancer 2 5.00 Disease 2 5.00 Adhesions 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In monocytes, B8, and to a lesser extent, its NO-free equivalent, B16, significantly inhibited TNF?

B16 Negative_regulation (inhibited) of B8 in monocytes

1) Confidence 0.01 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2525633 Disease Relevance 0.07 Pain Relevance 0.10

General Comments

This test has worked.