INT244858

Context Info Confidence 0.28 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.09 Pain Relevance 0.17

cell differentiation (Lbx1) extracellular space (C6) nucleus (Lbx1) DNA binding (Lbx1)

Lbx1 (Mus musculus) C6 (Mus musculus)

Pain Link Frequency Relevance Heat Spinal cord 2 93.44 Pain 1 86.68 substantia gelatinosa 2 63.88 Dorsal horn neuron 1 5.00 Central nervous system 1 5.00

Disease Link Frequency Relevance Heat Pain 1 86.68 Targeted Disruption 6 5.00 Apoptosis 2 5.00 Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Three Hox genes (a4, b2, and b8) were activated and ten Hox genes (c6, c8, c9, c10, c13, d1, d8, d9, and d10) were repressed by Lbx1.

Lbx1 Negative_regulation (repressed) of c6

1) Confidence 0.28 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.09 Pain Relevance 0.17

General Comments

This test has worked.