INT245171

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.61
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (MDK) signal transduction (MDK) extracellular region (MDK)
Anatomy Link Frequency
CFPAC-1 1
MDK (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 144 95.04 Very High Very High Very High
corticosteroid 24 76.56 Quite High
Inflammation 6 5.00 Very Low Very Low Very Low
palliative 3 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 153 99.24 Very High Very High Very High
Rheumatoid Arthritis 138 95.40 Very High Very High Very High
Infection 33 73.04 Quite High
Cancer 111 55.12 Quite High
Adenovirus Infection 3 40.32 Quite Low
Bronchopulmonary Dysplasia 27 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 15 5.00 Very Low Very Low Very Low
Toxicity 9 5.00 Very Low Very Low Very Low
Suicidal Behaviour 9 5.00 Very Low Very Low Very Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transcriptional activity of the midkine promoter in human pancreatic cancer cells
Transcription (activity) of midkine associated with pancreatic cancer
1) Confidence 0.35 Published 2008 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2529268 Disease Relevance 0.56 Pain Relevance 0
Transcriptional activity of the midkine promoter in human pancreatic cancer cells
Transcription (Transcriptional) of midkine associated with pancreatic cancer
2) Confidence 0.35 Published 2008 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2529268 Disease Relevance 0.57 Pain Relevance 0
Transcriptional activity of midkine promoter in CFPAC-1 cells was low, but it was higher compared to that of MIAPaCa-2 cells.
Transcription (activity) of midkine in CFPAC-1
3) Confidence 0.27 Published 2008 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2529268 Disease Relevance 0.39 Pain Relevance 0
MK mRNA and protein expression in response to different treatment were determined by Northern and Western blots.
Transcription (expression) of MK
4) Confidence 0.26 Published 2009 Journal Respir Res Section Abstract Doc Link PMC2739515 Disease Relevance 0.48 Pain Relevance 0.34
Data from the three control groups (no treatment, saline and CSO treatment) were combined since the vehicle treatments had no effect on MK mRNA expression.
Transcription (expression) of MK
5) Confidence 0.26 Published 2009 Journal Respir Res Section Body Doc Link PMC2739515 Disease Relevance 0.29 Pain Relevance 0.26
These data confirmed that no relationship exists between steady state mRNA and protein levels for MK [8].


Transcription (levels) of MK
6) Confidence 0.23 Published 2009 Journal Respir Res Section Body Doc Link PMC2739515 Disease Relevance 0.33 Pain Relevance 0.17

General Comments

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