INT245727

Context Info Confidence 0.00 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.57 Pain Relevance 0

cytosol (SUGT1) mitosis (SUGT1) cytoskeleton (DISC1) cytoplasm (DISC1)

SUGT1 (Homo sapiens) DISC1 (Homo sapiens)

Pain Link Frequency Relevance Heat backache 8 5.00 inflammatory 6 5.00 Pain 4 5.00 COX2 2 5.00 cytokine 2 5.00 Rheumatoid arthritis 2 5.00 osteoarthritis 2 5.00 imagery 2 5.00 Sciatica 2 5.00

Disease Link Frequency Relevance Heat Intervertebral Disk Degeneration 78 100.00 Disease 66 96.68 Aging 2 77.80 Spinal Osteophytosis 4 70.64 Low Back Pain 8 5.00 INFLAMMATION 6 5.00 Nicotine Addiction 6 5.00 Obesity 4 5.00 Pain 4 5.00 Scheuermann's Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Videman et al 37 and Kawaguchi et al 38 reported that subjects with the tt or Tt allele of the vitamin-D receptor gene were more frequently associated with multilevel and severe disc degeneration and disc herniation than ones with the TT allele.

allele Binding (associated) of disc associated with intervertebral disk degeneration

1) Confidence 0.00 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.79 Pain Relevance 0

Videman et al 37 and Kawaguchi et al 38 reported that subjects with the tt or Tt allele of the vitamin-D receptor gene were more frequently associated with multilevel and severe disc degeneration and disc herniation than ones with the TT allele.

allele Binding (associated) of disc associated with intervertebral disk degeneration

2) Confidence 0.00 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.78 Pain Relevance 0

General Comments

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