INT245732

Context Info Confidence 0.07 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.34 Pain Relevance 0.08

extracellular region (COL9A2) cytoskeleton (DISC1) cytoplasm (DISC1)

COL9A2 (Homo sapiens) DISC1 (Homo sapiens)

Pain Link Frequency Relevance Heat Osteoarthritis 2 59.20 rheumatoid arthritis 2 57.28 backache 8 5.00 Inflammation 6 5.00 Pain 4 5.00 COX2 2 5.00 cytokine 2 5.00 imagery 2 5.00 Sciatica 2 5.00

Disease Link Frequency Relevance Heat Intervertebral Disk Degeneration 78 100.00 Disease 66 99.96 Osteoarthritis 2 59.20 Rheumatoid Arthritis 2 57.28 Chondrodysplasia 2 54.56 Targeted Disruption 2 14.96 Low Back Pain 8 5.00 INFLAMMATION 6 5.00 Nicotine Addiction 6 5.00 Obesity 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

However, association of a COL9A2 specific haplotype with lumbar disc degeneration was detected.

COL9A2 Binding (association) of lumbar disc associated with intervertebral disk degeneration

1) Confidence 0.07 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.61 Pain Relevance 0.03

Accordingly, the allelic variation of COL9A2 that is associated with lumbar disc disease is dependent on race and nationality. 4.1.2 COL9A3

COL9A2 Binding (associated) of lumbar disc associated with disease

2) Confidence 0.06 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2532796 Disease Relevance 0.73 Pain Relevance 0.06

General Comments

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