INT245793

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.26
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL5A2) molecular_function (COL5A2)
Anatomy Link Frequency
cornea 2
COL5A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 10 51.48 Quite High
Pain 11 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Acute pain 2 5.00 Very Low Very Low Very Low
transcutaneous nerve stimulation 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wound Healing 4 78.88 Quite High
Death 2 74.76 Quite High
Osteoarthritis 26 51.48 Quite High
Apoptosis 8 18.32 Low Low
Pain 13 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Hypercalcemia 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, the data here presented indicate a marked decrease in proteoglycan synthesis and changes in corneal collagen organization 24 h after in vitro LASIK surgery in human cornea.



Regulation (changes) of Localization (organization) of collagen in cornea
1) Confidence 0.34 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2533033 Disease Relevance 0.15 Pain Relevance 0
Osteochondral explants were fixed and decalcified for 4 weeks and subsequently embedded in paraffin, while collagen gel samples were fixed overnight in a phosphate-buffered solution of 4% Para formaldehyde and embedded in paraffin. 5 ?
Regulation (fixed) of Localization (samples) of collagen
2) Confidence 0.06 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC2921357 Disease Relevance 0.05 Pain Relevance 0.03
Osteochondral explants were fixed and decalcified for 4 weeks and subsequently embedded in paraffin, while collagen gel samples were fixed overnight in a phosphate-buffered solution of 4% Para formaldehyde and embedded in paraffin. 5 ?
Regulation (embedded) of Localization (samples) of collagen
3) Confidence 0.06 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC2921357 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

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