INT246363

Context Info Confidence 0.02 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.40 Pain Relevance 0.06

cytosol (GBP2) plasma membrane (GBP2) nucleus (SETBP1) GTPase activity (GBP2) DNA binding (SETBP1)

SETBP1 (Homo sapiens) GBP2 (Homo sapiens)

Pain Link Frequency Relevance Heat headache 2 60.84 adenocard 4 45.00 cytokine 18 43.36 Inflammatory mediators 4 5.00 Inflammation 4 5.00 chemokine 2 5.00

Disease Link Frequency Relevance Heat Apoptosis 12 79.04 Bacillus Anthracis Infection 44 78.76 Cough 2 61.28 Headache 2 60.84 Fever 2 60.44 Hypoxia 4 39.96 Bordatella Infection 2 24.04 Yersinia Infection 36 5.00 Infection 20 5.00 Venezuelan Equine Encephalomyelitis 18 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Among all the pathogens studied so far, SEB was found to be the only pathogen to dramatically alter GBP-2.

SEB Regulation (alter) of GBP-2

1) Confidence 0.02 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2542375 Disease Relevance 0.14 Pain Relevance 0

2GBP-2 was a gene that was identified as being massively up regulated by SEB using differential display PCR (C.

SEB Regulation (regulated) of 2GBP-2

2) Confidence 0.01 Published 2008 Journal BMC Infect Dis Section Body Doc Link PMC2542375 Disease Relevance 0.26 Pain Relevance 0.06

General Comments

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