INT24668

Context Info Confidence 0.14 First Reported 1989 Last Reported 1989 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.25 Pain Relevance 0.16

extracellular region (COL7A1, EGF) signal transduction (EGF) extracellular space (EGF) cell adhesion (COL7A1) plasma membrane (EGF)

Anatomy Link Frequency skin 1 COL7A1 (Homo sapiens) EGF (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 2 100.00

Disease Link Frequency Relevance Heat Wound Healing 2 97.44 Injury 2 95.24

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Specific binding of biotinylated HBGF2, EGF, or other biologically active molecules (antibiotics, NSAIDs) to implantable collagen may provide a mechanism for positive therapeutic modulation of wound healing, including repair of full-thickness skin wounds with cultured cell-collagen composite grafts.

collagen Binding (binding) of EGF in skin associated with injury, wound healing and cinod

1) Confidence 0.14 Published 1989 Journal J. Surg. Res. Section Abstract Doc Link 2469861 Disease Relevance 0.19 Pain Relevance 0.10

Binding of biotinylated HBGF2 and EGF was specific (*, P less than 0.05), proportional to the concentration of biotinylated collagen, and resistant to ionic (NaCl) displacement.

collagen Binding (Binding) of EGF

2) Confidence 0.14 Published 1989 Journal J. Surg. Res. Section Abstract Doc Link 2469861 Disease Relevance 0.06 Pain Relevance 0.06

General Comments

This test has worked.