INT247095

Context Info Confidence 0.03 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.91 Pain Relevance 0.37

peptidase activity (F7) extracellular space (F7) extracellular region (F7) plasma membrane (F7)

F7 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 7 91.48 cytokine 8 70.32 cva 6 69.92 addiction 22 61.68 Inflammatory response 2 55.48 Morphine 18 23.16 Onset of action 3 5.00 Codeine 2 5.00 Analgesic 1 5.00 opiate 1 5.00

Disease Link Frequency Relevance Heat Myocardial Infarction 3 93.68 INFLAMMATION 9 91.48 Metabolic Syndrome 1 89.16 Diabetes Mellitus 8 88.20 Stroke 2 87.80 Disorder Of Lipid Metabolism 10 87.04 Disease 3 85.92 Coagulation Disorder 2 77.40 Infection 3 76.88 Increased Venous Pressure Under Development 1 75.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A preliminary multi-locus analysis using multifactor dimensionality reduction (MDR) analysis revealed an interesting association between FV (rs2187952) and FVII (rs3211719) within the complement and coagulation cascade that suggests that there may be both an interaction among genes within the pathway and heterogeneity among these genes (Figure 1).

FVII Binding (association) of

1) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2553267 Disease Relevance 0.38 Pain Relevance 0.17

The presenting association between Fibrinogen and CHD beyond 10 years may imply a casual effect and also there is association between Factor VII and CHD[9].

Factor VII Binding (association) of

2) Confidence 0.01 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2588593 Disease Relevance 1.52 Pain Relevance 0.21

General Comments

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