INT248181

Context Info Confidence 0.49 First Reported 2008 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0 Pain Relevance 0.03

cytosol (Hprt1) transferase activity, transferring glycosyl groups (Hprt1) cytoplasm (Hprt1)

Hprt1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat sodium channel 3 62.44 chemokine 9 50.00 Neuronal excitability 1 50.00 antidepressant 35 5.00 Action potential 17 5.00 Endep 16 5.00 Inflammation 14 5.00 Pain 14 5.00 Neuropathic pain 9 5.00 imagery 8 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 17 5.00 Pain 15 5.00 Neuropathic Pain 12 5.00 Nociception 9 5.00 Nervous System Injury 3 5.00 Myelodysplastic Syndromes 2 5.00 Anaplastic Astrocytoma 1 5.00 Targeted Disruption 1 5.00 Body Weight 1 5.00 Ganglion Cysts 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Copy number for each molecule (all P2X subunits and Lyn tyrosine kinase) was determined based on comparisons to standard curves, and for each sample, the copy number for each molecule was normalized to the expression of the endogenous housekeeping gene hypoxanthine phosphoribosyl transferase (HPRT).

Positive_regulation (normalized) of Gene_expression (expression) of hypoxanthine phosphoribosyl transferase

1) Confidence 0.49 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0

Fluorescence was normalized with the reference dye ROX, and gene expression was normalized to the housekeeping gene hypoxanthine ribosyltransferase (HPRT; [25]), run on the same plate.

Positive_regulation (ribosyltransferase) of Gene_expression (ribosyltransferase) of HPRT

2) Confidence 0.18 Published 2008 Journal Mol Pain Section Body Doc Link PMC2562993 Disease Relevance 0 Pain Relevance 0.03

General Comments

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