INT249488

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ephb1, Src) plasma membrane (Ephb1, Src) endosome (Ephb1)
mitochondrion (Src) enzyme binding (Src) response to stress (Src)
Anatomy Link Frequency
dorsal horns 2
Ephb1 (Rattus norvegicus)
Src (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 30 100.00 Very High Very High Very High
nMDA receptor 28 97.00 Very High Very High Very High
nMDA receptor antagonist 2 94.84 High High
Thermal hyperalgesia 13 90.12 High High
intrathecal 16 87.16 High High
allodynia 7 85.44 High High
Dorsal horn 11 85.32 High High
Eae 10 83.52 Quite High
Pain 6 71.60 Quite High
central sensitization 5 61.84 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 25 90.12 High High
Neuropathic Pain 18 85.44 High High
Inflammatory Pain 7 83.52 Quite High
Nociception 14 82.12 Quite High
Pain 13 71.60 Quite High
INFLAMMATION 9 55.00 Quite High
Ganglion Cysts 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Nervous System Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism apparently involved Src family kinases, since the level of phospho-Src bound to EphB receptors in the dorsal horns of the spinal cord was increased.
Positive_regulation (increased) of EphB Binding (bound) of phospho-Src in dorsal horns associated with spinal cord
1) Confidence 0.23 Published 2008 Journal Neuroscience Section Body Doc Link PMC2568875 Disease Relevance 0.68 Pain Relevance 1.12

General Comments

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