INT249863

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gpr17) plasma membrane (Gpr17) signal transducer activity (Gpr17)
Anatomy Link Frequency
neurons 2
Gpr17 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 16 5.00 Very Low Very Low Very Low
agonist 13 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Middle Cerebral Artery Infarction 29 88.36 High High
Death 12 62.64 Quite High
Cv Unclassified Under Development 11 5.00 Very Low Very Low Very Low
Brain Injury 9 5.00 Very Low Very Low Very Low
Brain Hemorrhage 8 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low
Demyelinating Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data show that after up-regulation in neurons, there is a second wave of GPR17 induction in microglia/macrophages as soon as these cells are activated and recruited toward the lesioned area as a consequence of damage.
Regulation (regulation) of Positive_regulation (induction) of GPR17 in neurons
1) Confidence 0.35 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2570486 Disease Relevance 0.41 Pain Relevance 0

General Comments

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