INT249959

Context Info Confidence 0.00 First Reported 2008 Last Reported 2008 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.04

cytosol (NOS1) peptidase activity (Cpa1) extracellular space (Cpa1) oxidoreductase activity (NOS1) extracellular region (Cpa1) cytoskeleton (NOS1)

Anatomy Link Frequency CPA 1 Cpa1 (Mus musculus) NOS1 (Homo sapiens)

Pain Link Frequency Relevance Heat withdrawal 1 86.12 addiction 1 44.00 Inflammation 4 5.00 cva 3 5.00 narcan 1 5.00 cytokine 1 5.00 Morphine 1 5.00 Bioavailability 1 5.00 Inflammatory mediators 1 5.00

Disease Link Frequency Relevance Heat Hepatotoxicity 1 81.84 INFLAMMATION 5 5.00 Hematological Disease 4 5.00 Thrombocytopenia 3 5.00 Hemorrhage 3 5.00 Body Weight 2 5.00 Aplasia 2 5.00 Adhesions 2 5.00 Stress 2 5.00 Hyperplasia 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interestingly, immunosuppressive effects of CPA are more pronounced on 18 day pt, than 9 day pt, indicating to an efficiency of low doses of CPA, which also up-regulate of NOS/NO system of marrow and blood.

CPA Neg (NO) Regulation (regulate) of NOS in CPA

1) Confidence 0.00 Published 2008 Journal The Open Biochemistry Journal Section Body Doc Link PMC2570548 Disease Relevance 0.08 Pain Relevance 0.04

General Comments

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