INT250575

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (APOBEC2) RNA binding (APOBEC2)
APOBEC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 32 99.52 Very High Very High Very High
Coronary Artery Disease 96 98.48 Very High Very High Very High
Lactose Intolerance 2 96.68 Very High Very High Very High
Cardiovascular Disease 140 90.80 High High
Adhesions 2 70.80 Quite High
Obesity 16 63.44 Quite High
Stroke 66 61.80 Quite High
Genetic Predisposition To Disease 2 59.20 Quite High
Disease 26 26.56 Quite Low
Metabolic Syndrome 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also studied one novel gene, apolipoprotein B mRNA editing enzyme (APOBEC2), which is located directly under a linkage peak (lod score of 4.44) for total cholesterol in our linkage study of 5775 individuals from twin families from the GenomEUtwin (www.genomeutwin.org).
Positive_regulation (located) of APOBEC2 associated with disorder of lipid metabolism
1) Confidence 0.43 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.69 Pain Relevance 0
A variant in the APOBEC2 gene, rs2395754, was associated with CHD in both prevalent and incident male cases (HR?
Positive_regulation (variant) of APOBEC2 associated with coronary artery disease
2) Confidence 0.43 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.87 Pain Relevance 0

General Comments

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