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Context Info
Confidence 0.37
First Reported 1987
Last Reported 1994
Negated 1
Speculated 1
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.48
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (Msh2) ATPase activity (Msh2) nucleus (Msh2)
enzyme binding (Msh2) cell cycle (Msh2) DNA binding (Msh2)
Anatomy Link Frequency
blood 2
Msh2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 2 100.00 Very High Very High Very High
Intracerebroventricular 2 99.00 Very High Very High Very High
Morphine 3 81.28 Quite High
narcan 4 77.04 Quite High
antagonist 2 72.24 Quite High
Opioid 1 70.48 Quite High
opioid receptor 1 67.36 Quite High
opiate 1 58.16 Quite High
Central nervous system 1 46.68 Quite Low
cva 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pressure Volume 2 Under Development 1 97.20 Very High Very High Very High
Hypotension 2 95.44 Very High Very High Very High
Appetite Loss 2 75.12 Quite High
Heart Rate Under Development 1 63.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A two flavour, unbiased, taste preference conditioning procedure was used to test for possible motivating effects of gamma 2-MSH.
Spec (possible) Regulation (effects) of 2-MSH
1) Confidence 0.37 Published 1989 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 2506600 Disease Relevance 0.15 Pain Relevance 0.34
Effect of ACTH-(4-10) and gamma 2-MSH on blood pressure after intracerebroventricular and intracisternal administration.
Regulation (Effect) of gamma 2-MSH in blood associated with anesthesia and intracerebroventricular
2) Confidence 0.35 Published 1993 Journal J. Cardiovasc. Pharmacol. Section Title Doc Link 7687715 Disease Relevance 0 Pain Relevance 0.20
The responses were maximal after 3-4 min and lasted for about 15 min. gamma 2-MSH had no effect when injected into the AP.
Neg (no) Regulation (effect) of 2-MSH
3) Confidence 0.29 Published 1994 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 8139700 Disease Relevance 0.23 Pain Relevance 0
The effect of intracerebroventricularly (i.c.v.) administered alpha-melanocyte-stimulating hormone (MSH) and gamma 2-MSH on hypothalamic blood flow autoregulation was studied in anesthetized rats at different levels of standardized arterial hypotension.
Regulation (autoregulation) of 2-MSH in blood associated with pressure volume 2 under development
4) Confidence 0.22 Published 1987 Journal Brain Res. Section Abstract Doc Link 2825914 Disease Relevance 0.10 Pain Relevance 0.15

General Comments

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