INT252145

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| style="color: black; background:#AAFCFB; white-space:wrap;"| '''Pain Relations:'''
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
(frequency)
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Thalamus]] (4)
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
{{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hippocampus]] (43)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[isoflurane]] (8)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Glutamate]] (2)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[gABA]] (1)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Catecholamines]] (17)
+
{{#icon: cold.png|Low}} {{#icon: cold.png|Low}}
+
 
|-
 
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| style="color: black; background:#AAFCFB; white-space:wrap;"| '''Disease Relations:'''
 
 
(frequency)
 
(frequency)
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dislocations]] (1)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Thalamus]]
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Tremor]] (16)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.4
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Decapitation]] (9)
+
|-
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hippocampus]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Retina Disease]] (8)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 43
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 67.12
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Alcohol Intoxication]] (8)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cognitive Disorder]] (56)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[isoflurane]]
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
|}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 63.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Glutamate]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 61.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[gABA]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60.8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Catecholamine]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 17
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 18.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Low}} {{#icon: cold.png|Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[anesthesia]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cholecystokinin]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 48
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[amygdala]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[alcohol]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
  
 +
|}|
 +
|
 +
{| cellspacing=1 cellpadding=5 align=center
 +
|-
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dislocations]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Tremor]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Decapitation]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 9
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Retina Disease]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Alcohol Intoxication]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cognitive Disorder]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neurodegenerative Disease]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Stress]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Disseminated Intravascular Coagulation]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Leukemia]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
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Revision as of 11:01, 12 September 2012

Context Info
Confidence 0.3261196600
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in NULL
Documents 9
Total Number 9

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Snap25) transport (Napb) vesicle-mediated transport (Napb)
plasma membrane (Snap25) cytoplasm (Snap25)
Anatomy Mention Frequency
neurons 3
plasma 2
bands 1
Napb (Mus musculus)
Snap25 (Mus musculus)
(frequency)
Pain Term Frequency Confidence Heat
Thalamus 4 91.4 High High
Hippocampus 43 67.12 Quite High
isoflurane 8 63.36 Quite High
Glutamate 2 61.36 Quite High
gABA 1 60.8 Quite High
Catecholamine 17 18.36 Low Low
anesthesia 8 5 Very Low Very Low Very Low
Cholecystokinin 48 5 Very Low Very Low Very Low
amygdala 8 5 Very Low Very Low Very Low
alcohol 1 5 Very Low Very Low Very Low
|
Disease Term Frequency Confidence Heat
Dislocations 1 5 Very Low Very Low Very Low
Tremor 16 5 Very Low Very Low Very Low
Decapitation 9 5 Very Low Very Low Very Low
Retina Disease 8 5 Very Low Very Low Very Low
Alcohol Intoxication 8 5 Very Low Very Low Very Low
Cognitive Disorder 56 5 Very Low Very Low Very Low
Neurodegenerative Disease 16 5 Very Low Very Low Very Low
Stress 8 5 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 8 5 Very Low Very Low Very Low
Leukemia 1 5 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Event Anatomy Negation Speculation Pain term
Taken together with other studies [5,10,11], these results provide additional evidence that SNAP-25b is a key component of the neural SNARE complex responsible for both GABAergic and glutamatergic transmission in mature neurons.


SNARE Binding (complex) of SNAP-25b in neurons
1) Confidence 0.194688144144247 Published 2008 Journal N/A Section N/A Doc Link PMC2600647
The different stability of SNARE complexes found in neo-excised SNAP-25b deficient mutants compared to WT mice (Figure 2E) and that SNAP-25b demonstrates an increased association with plasma membrane fractions compared to SNAP-25a (see Text S1, Figure S2) suggest that SNAP-25a and SNAP-25b are differently associated with SNARE complexes close to, or immediately upstream of fusion.
SNARE Binding (associated) of SNAP-25a in plasma
2) Confidence 0.131431529950277 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
The different stability of SNARE complexes found in neo-excised SNAP-25b deficient mutants compared to WT mice (Figure 2E) and that SNAP-25b demonstrates an increased association with plasma membrane fractions compared to SNAP-25a (see Text S1, Figure S2) suggest that SNAP-25a and SNAP-25b are differently associated with SNARE complexes close to, or immediately upstream of fusion.
SNARE Binding (associated) of SNAP-25b in plasma
3) Confidence 0.131431529950277 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
To measure the grade of disassembly of heat-resistant SNARE complex in WT and SNAP-25b KO tissue, percentage monomeric SNAP-25 protein of total SNAP-25 in ternary complex at 4°C was calculated and compared with the value calculated at a certain temperature.
SNARE Binding (complex) of SNAP-25
4) Confidence 0.119227494325505 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
To measure the grade of disassembly of heat-resistant SNARE complex in WT and SNAP-25b KO tissue, percentage monomeric SNAP-25 protein of total SNAP-25 in ternary complex at 4°C was calculated and compared with the value calculated at a certain temperature.
SNARE Binding (complex) of SNAP-25b
5) Confidence 0.119227494325505 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
500,000) was used to detect immunoreactivity of bands migrating as ternary SNARE complex or solitaire SNAP-25 protein.
SNARE Binding (complex) of SNAP-25 protein in bands
6) Confidence 0.119227494325505 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
In the SNARE complex with syntaxin and VAMP, SNAP-25 contributes with two amphipathic ?
SNARE Binding (complex) of SNAP-25
7) Confidence 0.114605754376932 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
The SNAP-25b(Bdr) SNARE complexes, apparently more stable than complexes with WT SNAP-25b, result in impairment of both spontaneous and evoked release from cortical neurons and lack of facilitation during trains of high-frequency stimulation [48].
SNARE Binding (complexes) of SNAP-25b in neurons
8) Confidence 0.114605754376932 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
The SNAP-25b(Bdr) SNARE complexes, apparently more stable than complexes with WT SNAP-25b, result in impairment of both spontaneous and evoked release from cortical neurons and lack of facilitation during trains of high-frequency stimulation [48].
SNARE Binding (complexes) of SNAP-25b in neurons
9) Confidence 0.114605754376932 Published 2008 Journal N/A Section N/A Doc Link PMC2581893

General Comments

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