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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Disease Relevance
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 0.84988
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 0.85
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Pain Relevance
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 1.50464
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 0.75
 
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{| cellspacing=2 cellpadding=2
 
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
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| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Thalamus]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Thalamus]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.4
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.40
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
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| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[isoflurane]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[isoflurane]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.6
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.60
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
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| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[gABA]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[gABA]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60.8
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 60.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Action potential]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Action potential]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 11
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
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|
 
|
|
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
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| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Tremor]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Tremor]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.8
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.80
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
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| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dislocations]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Dislocations]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Decapitation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Decapitation]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 9
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 9
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neurodegenerative Disease]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Neurodegenerative Disease]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 16
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Stress]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Stress]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
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|}
 
{| style="color: black; background-color: white;" cellpadding=6 cellspacing=6 class="wikitable"
 
{| style="color: black; background-color: white;" cellpadding=6 cellspacing=6 class="wikitable"
| Taken together with other studies [5,10,11], these results provide additional evidence that <span style="background-color:#FFFF00">SNAP-25b</span> is a key component of the neural <span style="background-color:#FFFF00">SNARE</span> <span style="background-color:#B0E0E6">complex</span> responsible for both GABAergic and glutamatergic transmission in mature <span style="background-color:#FFDEAD">neurons</span>.
+
| Taken together with other studies [5,10,11], these results provide additional evidence that <span style="background-color:#FFFF00">SNAP-25b</span> is a key component of the neural <span style="background-color:#FFFF00">SNARE</span> <span style="background-color:#B0E0E6">complex</span> responsible for both <span style="background-color:#FFA07A">GABAergic</span> and glutamatergic transmission in mature <span style="background-color:#FFDEAD">neurons</span>.
  
  
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{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''SNARE'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">complex</span>) of <span style="color:#800000">'''SNAP-25b'''</span> in <span style="color:#808000">neurons</span>
+
| <span style="color:#800000">'''SNARE'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">complex</span>) of <span style="color:#800000">'''SNAP-25b'''</span> in <span style="color:#808000">neurons</span> associated with <span style="color:#FF0000">'''gabaergic'''</span>
 
|-
 
|-
 
|}
 
|}
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2600647 PMC2600647]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2600647 PMC2600647]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.39
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.04
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.04
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
|}
 
|}
 
|-
 
|-
Line 465: Line 465:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.13
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.04
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.36
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
|}
 
|}
 
|-
 
|-
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2581893 PMC2581893]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.36
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
|}
 
|}
 
|-
 
|-

Revision as of 12:21, 14 September 2012

Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 0.85
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Snap25) transport (Napb) vesicle-mediated transport (Napb)
plasma membrane (Snap25) cytoplasm (Snap25)
Anatomy Mention Frequency
neurons 3
plasma 2
bands 1
Napb (Mus musculus)
Snap25 (Mus musculus)
Pain Term Frequency Confidence Heat
GABAergic 45 99.12 Very High Very High Very High
Thalamus 4 91.40 High High
Pyramidal cell 24 78.08 Quite High
Neurotransmitter 27 77.52 Quite High
isoflurane 8 75.60 Quite High
Hippocampus 43 75.44 Quite High
Catecholamine 17 66.68 Quite High
Glutamate 2 61.36 Quite High
gABA 1 60.80 Quite High
Action potential 11 50.00 Quite Low
Disease Term Frequency Confidence Heat
Ataxia 8 92.72 High High
Sprains And Strains 17 91.36 High High
Retina Disease 8 89.64 High High
Alcohol Intoxication 8 88.08 High High
Tremor 16 72.80 Quite High
Cognitive Disorder 56 55.72 Quite High
Dislocations 1 5.00 Very Low Very Low Very Low
Decapitation 9 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 16 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together with other studies [5,10,11], these results provide additional evidence that SNAP-25b is a key component of the neural SNARE complex responsible for both GABAergic and glutamatergic transmission in mature neurons.


SNARE Binding (complex) of SNAP-25b in neurons associated with gabaergic
1) Confidence 0.19 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2600647 Disease Relevance 0 Pain Relevance 0.39
The different stability of SNARE complexes found in neo-excised SNAP-25b deficient mutants compared to WT mice (Figure 2E) and that SNAP-25b demonstrates an increased association with plasma membrane fractions compared to SNAP-25a (see Text S1, Figure S2) suggest that SNAP-25a and SNAP-25b are differently associated with SNARE complexes close to, or immediately upstream of fusion.
SNARE Binding (associated) of SNAP-25a in plasma
2) Confidence 0.13 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0 Pain Relevance 0.08
The different stability of SNARE complexes found in neo-excised SNAP-25b deficient mutants compared to WT mice (Figure 2E) and that SNAP-25b demonstrates an increased association with plasma membrane fractions compared to SNAP-25a (see Text S1, Figure S2) suggest that SNAP-25a and SNAP-25b are differently associated with SNARE complexes close to, or immediately upstream of fusion.
SNARE Binding (associated) of SNAP-25b in plasma
3) Confidence 0.13 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0 Pain Relevance 0.08
To measure the grade of disassembly of heat-resistant SNARE complex in WT and SNAP-25b KO tissue, percentage monomeric SNAP-25 protein of total SNAP-25 in ternary complex at 4°C was calculated and compared with the value calculated at a certain temperature.
SNARE Binding (complex) of SNAP-25
4) Confidence 0.12 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0 Pain Relevance 0.04
To measure the grade of disassembly of heat-resistant SNARE complex in WT and SNAP-25b KO tissue, percentage monomeric SNAP-25 protein of total SNAP-25 in ternary complex at 4°C was calculated and compared with the value calculated at a certain temperature.
SNARE Binding (complex) of SNAP-25b
5) Confidence 0.12 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0 Pain Relevance 0.04
500,000) was used to detect immunoreactivity of bands migrating as ternary SNARE complex or solitaire SNAP-25 protein.
SNARE Binding (complex) of SNAP-25 protein in bands
6) Confidence 0.12 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0 Pain Relevance 0.03
In the SNARE complex with syntaxin and VAMP, SNAP-25 contributes with two amphipathic ?
SNARE Binding (complex) of SNAP-25
7) Confidence 0.11 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0.13 Pain Relevance 0.04
The SNAP-25b(Bdr) SNARE complexes, apparently more stable than complexes with WT SNAP-25b, result in impairment of both spontaneous and evoked release from cortical neurons and lack of facilitation during trains of high-frequency stimulation [48].
SNARE Binding (complexes) of SNAP-25b in neurons
8) Confidence 0.11 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0.36 Pain Relevance 0.03
The SNAP-25b(Bdr) SNARE complexes, apparently more stable than complexes with WT SNAP-25b, result in impairment of both spontaneous and evoked release from cortical neurons and lack of facilitation during trains of high-frequency stimulation [48].
SNARE Binding (complexes) of SNAP-25b in neurons
9) Confidence 0.11 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581893 Disease Relevance 0.36 Pain Relevance 0.03

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