INT252145

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Revision as of 12:07, 12 September 2012

Context Info
Confidence 0.3261196600
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in NULL
Documents 9
Total Number 9

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Snap25) transport (Napb) vesicle-mediated transport (Napb)
plasma membrane (Snap25) cytoplasm (Snap25)
Anatomy Mention Frequency
neurons 3
plasma 2
bands 1
Napb (Mus musculus)
Snap25 (Mus musculus)
Pain Term Frequency Confidence Heat
Thalamus 4 91.4 High High
Hippocampus 43 67.12 Quite High
isoflurane 8 63.36 Quite High
Glutamate 2 61.36 Quite High
gABA 1 60.8 Quite High
Catecholamine 17 18.36 Low Low
anesthesia 8 5 Very Low Very Low Very Low
Cholecystokinin 48 5 Very Low Very Low Very Low
amygdala 8 5 Very Low Very Low Very Low
alcohol 1 5 Very Low Very Low Very Low
|
Disease Term Frequency Confidence Heat
Dislocations 1 5 Very Low Very Low Very Low
Tremor 16 5 Very Low Very Low Very Low
Decapitation 9 5 Very Low Very Low Very Low
Retina Disease 8 5 Very Low Very Low Very Low
Alcohol Intoxication 8 5 Very Low Very Low Very Low
Cognitive Disorder 56 5 Very Low Very Low Very Low
Neurodegenerative Disease 16 5 Very Low Very Low Very Low
Stress 8 5 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 8 5 Very Low Very Low Very Low
Leukemia 1 5 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Event Anatomy Negation Speculation Pain term
Taken together with other studies [5,10,11], these results provide additional evidence that SNAP-25b is a key component of the neural SNARE complex responsible for both GABAergic and glutamatergic transmission in mature neurons.


SNARE Binding (complex) of SNAP-25b in neurons
1) Confidence 0.194688144144247 Published 2008 Journal N/A Section N/A Doc Link PMC2600647
The different stability of SNARE complexes found in neo-excised SNAP-25b deficient mutants compared to WT mice (Figure 2E) and that SNAP-25b demonstrates an increased association with plasma membrane fractions compared to SNAP-25a (see Text S1, Figure S2) suggest that SNAP-25a and SNAP-25b are differently associated with SNARE complexes close to, or immediately upstream of fusion.
SNARE Binding (associated) of SNAP-25a in plasma
2) Confidence 0.131431529950277 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
The different stability of SNARE complexes found in neo-excised SNAP-25b deficient mutants compared to WT mice (Figure 2E) and that SNAP-25b demonstrates an increased association with plasma membrane fractions compared to SNAP-25a (see Text S1, Figure S2) suggest that SNAP-25a and SNAP-25b are differently associated with SNARE complexes close to, or immediately upstream of fusion.
SNARE Binding (associated) of SNAP-25b in plasma
3) Confidence 0.131431529950277 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
To measure the grade of disassembly of heat-resistant SNARE complex in WT and SNAP-25b KO tissue, percentage monomeric SNAP-25 protein of total SNAP-25 in ternary complex at 4°C was calculated and compared with the value calculated at a certain temperature.
SNARE Binding (complex) of SNAP-25
4) Confidence 0.119227494325505 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
To measure the grade of disassembly of heat-resistant SNARE complex in WT and SNAP-25b KO tissue, percentage monomeric SNAP-25 protein of total SNAP-25 in ternary complex at 4°C was calculated and compared with the value calculated at a certain temperature.
SNARE Binding (complex) of SNAP-25b
5) Confidence 0.119227494325505 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
500,000) was used to detect immunoreactivity of bands migrating as ternary SNARE complex or solitaire SNAP-25 protein.
SNARE Binding (complex) of SNAP-25 protein in bands
6) Confidence 0.119227494325505 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
In the SNARE complex with syntaxin and VAMP, SNAP-25 contributes with two amphipathic ?
SNARE Binding (complex) of SNAP-25
7) Confidence 0.114605754376932 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
The SNAP-25b(Bdr) SNARE complexes, apparently more stable than complexes with WT SNAP-25b, result in impairment of both spontaneous and evoked release from cortical neurons and lack of facilitation during trains of high-frequency stimulation [48].
SNARE Binding (complexes) of SNAP-25b in neurons
8) Confidence 0.114605754376932 Published 2008 Journal N/A Section N/A Doc Link PMC2581893
The SNAP-25b(Bdr) SNARE complexes, apparently more stable than complexes with WT SNAP-25b, result in impairment of both spontaneous and evoked release from cortical neurons and lack of facilitation during trains of high-frequency stimulation [48].
SNARE Binding (complexes) of SNAP-25b in neurons
9) Confidence 0.114605754376932 Published 2008 Journal N/A Section N/A Doc Link PMC2581893

General Comments

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