INT252204

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Context Info
Confidence 0.70
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 0.06
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (GP9) plasma membrane (GP9)
Anatomy Link Frequency
bridges 1
GP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 7 61.24 Quite High
Disease Link Frequency Relevance Heat
Bites And Stings 7 62.68 Quite High
Aggression 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To dephosphorylate GP-9B, an aliquot (50 µl) of the isolated protein sample (see above) was analyzed by LC-ESI/MS before and after incubation with 1 unit of alkaline phosphatase (Sigma, St.
Phosphorylation (dephosphorylate) of GP-9B
1) Confidence 0.70 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
To identify a phosphorylated residue in GP-9B, an aliquot (200 µl) of the protein isolated by ion-exchange and gel filtration chromatography (see above) was dried in a SpeedVac and incubated with 25 µl of 8 M urea in 0.4 M ammonium bicarbonate, 2.3 µl of 100 mM DTT at 50°C for 15 min.
Phosphorylation (phosphorylated) of GP-9B
2) Confidence 0.61 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
Thus, we conclude that in marked contrast to the hitherto known pheromone-binding proteins, GP-9B undergoes phosphorylation and thus existed in two forms, phosphorylated GP-9B (pGP-9B, observed MM 14,810 Da) and dephosphorylated form (GP-9B, observed MM 14,730 Da).
Phosphorylation (phosphorylated) of GP-9
3) Confidence 0.61 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
GP-9B existed in two forms, one of them is phosphorylated.
Phosphorylation (phosphorylated) of GP-9B
4) Confidence 0.54 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2582448 Disease Relevance 0.06 Pain Relevance 0.06
We then reasoned that the difference in the observed and calculated molecular masses could be due to phosphorylation of GP-9B, in addition to formation of disulfide bridges.
Phosphorylation (phosphorylation) of GP-9B in bridges
5) Confidence 0.54 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
Thus, we conclude that in marked contrast to the hitherto known pheromone-binding proteins, GP-9B undergoes phosphorylation and thus existed in two forms, phosphorylated GP-9B (pGP-9B, observed MM 14,810 Da) and dephosphorylated form (GP-9B, observed MM 14,730 Da).
Phosphorylation (phosphorylated) of GP-9B
6) Confidence 0.54 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0
Thus, we conclude that in marked contrast to the hitherto known pheromone-binding proteins, GP-9B undergoes phosphorylation and thus existed in two forms, phosphorylated GP-9B (pGP-9B, observed MM 14,810 Da) and dephosphorylated form (GP-9B, observed MM 14,730 Da).
Phosphorylation (phosphorylation) of GP-9B
7) Confidence 0.54 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582448 Disease Relevance 0 Pain Relevance 0

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