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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.72
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd36, Cd47) plasma membrane (Cd36, Cd47) lipid binding (Cd36)
transport (Cd36) mitochondrion (Cd36) Golgi apparatus (Cd36)
Anatomy Link Frequency
blood 1
fibroblasts 1
Cd36 (Mus musculus)
Cd47 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 43 97.44 Very High Very High Very High
cytokine 8 90.28 High High
Kinase C 6 84.76 Quite High
rheumatoid arthritis 14 62.96 Quite High
psoriasis 1 42.68 Quite Low
chemokine 2 27.76 Quite Low
tolerance 6 14.56 Low Low
abatacept 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Synovitis 1 98.60 Very High Very High Very High
INFLAMMATION 43 97.44 Very High Very High Very High
Colitis 6 87.24 High High
Carcinoma 5 85.84 High High
Cleidocranial Dysplasia 3 85.24 High High
Retinoblastoma 1 81.28 Quite High
Stress 2 72.96 Quite High
Rheumatoid Arthritis 14 62.96 Quite High
Psoriasis 1 42.68 Quite Low
Disease 14 39.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, TSP1 has been reported to block the pro-angiogenic effects of nitric oxide (NO) in endothelial and vascular smooth muscle cells.(33) Low level of NO are anti-inflammatory, but in inflamed tissues the levels of NO increase and blood flow, vascular permeability and angiogenesis are enhanced.(11) By interacting with their receptors CD36 and CD47, TSP1 prevents the pro-angiogenic effects of NO and makes EC more susceptible to its inhibition.(33)
CD36 Binding (interacting) of CD47 in blood associated with inflammation
1) Confidence 0.10 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2600574 Disease Relevance 0.49 Pain Relevance 0.07
CD47 and thrombospondin can form a trimolecular complex with CD36 expressed on synovial fibroblasts.
CD36 Binding (complex) of CD47 in fibroblasts
2) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582810 Disease Relevance 0.23 Pain Relevance 0.12

General Comments

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