INT252806

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F2, CCL2) extracellular region (F2, CCL2) aging (CCL2)
cytoplasm (CCL2) peptidase activity (F2) signal transduction (CCL2)
F2 (Homo sapiens)
CCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 48 100.00 Very High Very High Very High
cytokine 21 100.00 Very High Very High Very High
chemokine 6 91.44 High High
Inflammatory response 11 79.92 Quite High
fibrosis 19 49.96 Quite Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 57 100.00 Very High Very High Very High
Injury 46 93.44 High High
Liver Disease 43 91.84 High High
Fibrosis 37 80.60 Quite High
Stress 107 79.00 Quite High
Cirrhosis 45 57.04 Quite High
Wound Healing 12 50.00 Quite Low
Death 55 5.00 Very Low Very Low Very Low
Apoptosis 55 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With regard to HSC/MFs, MCP-1 expression is stimulated by pro-inflammatory cytokines, such as IL-1 and TNF [282,283], thrombin [285], engagement of integrin receptors [285] and both ROS and HNE [273,286].
thrombin Positive_regulation (stimulated) of Gene_expression (expression) of MCP-1 associated with inflammation and cytokine
1) Confidence 0.01 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.80 Pain Relevance 0.27

General Comments

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