INT252938

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Context Info
Confidence 0.75
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Pttg1) chromosome organization (Pttg1) chromosome segregation (Pttg1)
nucleus (Pttg1) cell cycle (Pttg1) cell division (Pttg1)
Pttg1 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 18 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aneuploidy 16 98.52 Very High Very High Very High
Chromosomal Instability 8 97.88 Very High Very High Very High
Cancer 174 73.00 Quite High
Targeted Disruption 54 68.84 Quite High
Colon Cancer 4 62.88 Quite High
Apoptosis 36 62.00 Quite High
Ovarian Cancer 32 50.00 Quite Low
Repression 6 32.96 Quite Low
Pituitary Cancer 26 5.00 Very Low Very Low Very Low
Metastasis 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Wang et al. [49] reported that the securin in budding yeast is phosphorylated by Chk1 kinase, which may increase its stability and thereby block the cell cycle progression.
Phosphorylation (phosphorylated) of securin
1) Confidence 0.75 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.64 Pain Relevance 0
Similar to Chk1, in mammalian cells, Ku-70, an enzyme involved in DNA double-strand break repair, phosphorylates PTTG in vitro.
Phosphorylation (phosphorylates) of PTTG
2) Confidence 0.65 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.47 Pain Relevance 0

General Comments

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