INT253188

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gpx1) aging (Gpx1) lipid metabolic process (Gpx1)
cytoplasm (Gpx1) cytosol (Gpx1) cell proliferation (Gpx1)
Anatomy Link Frequency
embryo 1
Gpx1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 4 19.84 Low Low
Kinase C 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 10 96.88 Very High Very High Very High
Diabetes Mellitus 100 94.36 High High
Exencephaly /

Neural Tube Defects

4 83.44 Quite High
Apoptosis 20 83.12 Quite High
Parkinson's Disease 2 75.36 Quite High
Gestational Diabetes 18 66.80 Quite High
Congenital Anomalies 16 61.36 Quite High
INFLAMMATION 4 19.84 Low Low
Fetal Diseases 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Such an association has not been suggested before, to our knowledge, and the localization of Gpx-1 protein in the cardiac wall on day 11 may suggest the occurrence of a protective antioxidative mechanism.
Localization (localization) of Gpx-1
1) Confidence 0.73 Published 2008 Journal Diabetes Section Body Doc Link PMC2584142 Disease Relevance 0.52 Pain Relevance 0
In particular, the SODs, Gpx-1, and Shh genes decreased and VEGF increased in the Nm embryo, thus indicating a coupling to oxidative stress and neural crest cell development.
Localization (decreased) of Gpx-1 in embryo associated with stress
2) Confidence 0.68 Published 2008 Journal Diabetes Section Body Doc Link PMC2584142 Disease Relevance 0.70 Pain Relevance 0

General Comments

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