INT254017

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Latest revision as of 00:19, 22 September 2012

Context Info
Confidence 0.48
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.93
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Map2) intracellular (Map2) protein complex (Map2)
cytoplasm (Map2)
Anatomy Link Frequency
neuronal 2
neurons 2
Map2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 62 99.28 Very High Very High Very High
Nav1.2 1 82.52 Quite High
sSRI 10 80.56 Quite High
fluoxetine 20 79.96 Quite High
monoamine 5 74.88 Quite High
Serotonin 17 73.28 Quite High
cytokine 1 63.44 Quite High
Inflammatory response 1 56.80 Quite High
unmyelinated 1 52.40 Quite High
depression 15 51.36 Quite High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 50 99.28 Very High Very High Very High
Carcinoma 1 97.92 Very High Very High Very High
Injury 2 95.40 Very High Very High Very High
Death 13 81.88 Quite High
INFLAMMATION 2 56.80 Quite High
Aggression 1 56.08 Quite High
Affective Disorder 1 54.60 Quite High
Anxiety Disorder 1 53.64 Quite High
Depression 18 51.36 Quite High
Apoptosis 2 50.32 Quite High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, results suggest that MAP2 expression may be necessary for both neurite extension and cessation of cell division as the specific suppression of MAP2 synthesis prevents the neuronal differentiation of embryonic carcinoma cells exposed to retinoic acid, as shown by the absence of neurites [53].
Negative_regulation (suppression) of Gene_expression (synthesis) of MAP2 in neuronal associated with carcinoma
1) Confidence 0.48 Published 2010 Journal The Open Neurology Journal Section Body Doc Link PMC2928987 Disease Relevance 0.31 Pain Relevance 0.41
We also demonstrated clusters of IBA-1-expressing cells in the ischemic lesions where MAP2 staining was lost three days after ischemia and thereafter.
Negative_regulation (lost) of Gene_expression (staining) of MAP2 associated with ischemia
2) Confidence 0.33 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.61 Pain Relevance 0.22
Kv2.1 localization in a single proximal neurite with diminished MAP2 staining, i.e. the AIS (marked by the arrow in Fig. 3), was observed in 35% of 7 DIV neurons and 63% of 10 DIV neurons (200 neurons examined in each of three experiments).
Negative_regulation (diminished) of Gene_expression (staining) of MAP2 in neurons
3) Confidence 0.18 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2592246 Disease Relevance 0 Pain Relevance 0.11

[edit] General Comments

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