INT254570

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 6.72
Pain Relevance 5.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PAG1) plasma membrane (PAG1) intracellular (PAG1)
Anatomy Link Frequency
neurons 2
PAG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central grey 279 100.00 Very High Very High Very High
Rostral ventromedial medulla 153 100.00 Very High Very High Very High
Periaqueductal grey 86 100.00 Very High Very High Very High
Pain 84 96.76 Very High Very High Very High
Morphine 237 96.56 Very High Very High Very High
Hyperalgesia 29 96.00 Very High Very High Very High
mu opioid receptor 45 95.92 Very High Very High Very High
Lasting pain 24 93.44 High High
ascending facilitation 2 90.24 High High
Inflammation 15 89.28 High High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 373 100.00 Very High Very High Very High
Stress 16 99.36 Very High Very High Very High
Sprains And Strains 5 98.08 Very High Very High Very High
Anxiety Disorder 34 97.24 Very High Very High Very High
Pain 108 96.76 Very High Very High Very High
Hyperalgesia 29 96.00 Very High Very High Very High
Nociception 22 92.12 High High
Inflammatory Pain 15 89.28 High High
INFLAMMATION 12 73.36 Quite High
Overactive Bladder 4 49.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and ventrolateral subdivisions of the PAG and increased in density along the
Regulation (ventrolateral) of Gene_expression (subdivisions) of PAG associated with central grey
1) Confidence 0.35 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2633449 Disease Relevance 1.04 Pain Relevance 0.91
measure the activity of populations of PAG-RVM neurons in the PAG of males and females.
Regulation (populations) of Gene_expression (neurons) of PAG-RVM in neurons associated with central grey and rostral ventromedial medulla
2) Confidence 0.35 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2633449 Disease Relevance 1.28 Pain Relevance 1.64
and ventrolateral regions of the PAG, an area known to contain a dense distribution
Regulation (ventrolateral) of Gene_expression (regions) of PAG associated with central grey
3) Confidence 0.35 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2633449 Disease Relevance 1.45 Pain Relevance 1.51
In terms of PAG function,
Regulation (terms) of Gene_expression (function) of PAG associated with periaqueductal grey
4) Confidence 0.20 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2593562 Disease Relevance 1.30 Pain Relevance 0.73
regime elicits differential expression of the immediate early gene c-fos in the ventrolateral PAG in rats in
Regulation (differential) of Gene_expression (expression) of PAG associated with periaqueductal grey
5) Confidence 0.20 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2593562 Disease Relevance 1.65 Pain Relevance 0.97

General Comments

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